Human reproduction is basically the fusion of a sperm (from a male) and an egg (from a female). The development of an embryo is the same in all in embryos. The embryonic gonad (in an embryo) can either develop testes (and become a baby boy) or develop ovaries (and become a baby girl), so the development of a whole baby is dependent on one gene (presence or absence of it).
If the gene SRY is present, the embryonic gonad develops into testes. This gene is located on the Y chromosome (which is only found n males), so it's present in 50% of embryos. The SRY codes for a DNA-binding protein called TDF (testes determining factor). TDF stimulates the expression of other gene that causes the development of testis (which technically makes a man)
50% of embryos have 2 X chromosomes (found only in females) and no Y so they do not have a copy of the SRY gene (obviously). TDF is therefore not produced and embryonic gonads develop into ovaries.
But some times this process can go wrong, and a person may have the Y gene but the SRY isn't triggered so the the TDF can't be expressed. (So they have the chromosomes of a man (XY) but a body of a woman as the TDF was not expressed so there was no development of the testes, which is why they feel they way they do).
Hopefully you guys understand.... I tried to simplify it as much as possible. I wanted to post this on the forum hoping Onision would come across it and raise awareness because there is scientific evidence.
Last Edit: May 31, 2017 12:40:40 GMT -8 by yeetimout
That is not what I am "thinking" about. IK what I said. This is pulled straight out of my textbook soo...
This is so interesting, I had no idea. But another factor could be the thyroid.
That is true, there are a lot of factors to weight gain such as thyroid, but the most common and undetectable one is the PYY3-36 hormone deficiency. Also, there isn't much awareness on PYY3-36 hormone deficiency, so most people don't know. I am also guessing that there are some supplements that can be taken to control it, but I am not sure.
Last Edit: May 16, 2017 9:09:33 GMT -8 by yeetimout
I am no doctor or whatever but I just wanted to voice my opinion on this but I do take higher level biology. It's easy to say eat less? but for some people that is not an option. Why? It's because they lack the PYY3-36 hormone. There are three hormones that trigger the appetite control center (which is in the hypothalamus, in the brain), warning that the stomach is full. The three hormones are leptin, insulin and PYY3-36. If there isn't sufficient amount of PYY3-36, the person won't be able to stop eating since the appetite control center isn't triggered saying he/she is full. Because of this he/she gain weight at a quicker rate. This is obviously not the person's fault as it is the body's inability to to secrete the PYY3-36 hormone.